Division Highlights for 1997:

The Division of Pediatric Nephrology enjoyed a strong and successful year in 1997. The Casey Lee Ball Pediatric Nephrology Laboratories were dedicated in May. Here cutting-edge research is being conducted in the clinical and basic science aspects of osteodystrophy in children and adolescents with chronic renal failure, dialysis, and kidney transplants. Equally exciting studies are being conducted with the most innovative forms of immunosuppression in pediatric renal transplantation. In the area of clinical care, the Pediatric Dialysis Program, one of the nation's largest, has recently opened a new, dedicated Pediatric Hemodialysis. The Pediatric Renal Transplantation Program performed 30 kidney transplants in 1997, making it one of the largest pediatric kidney transplant programs in the United States. Both the Kidney Transplant and Dialysis Programs continue to have benchmark clinical outcomes that are significantly superior to national pediatric registry results reported to the North American Pediatric Renal Transplant Cooperative Study.

Finally, the education and training program of the Division of Pediatric Nephrology continues to train fellows who have been successful in academic Pediatric Nephrology. Dr. Beatriz Kuizon, a graduate of the fellowship program in June 1997, and our newest UCLA faculty member, was awarded a National Kidney Foundation Clinical Investigator Award. Dr. Alan Shapiro, a first-year fellow, was awarded a prestigious Pediatric Scientist Development Award.

ETTENGER, ROBERT B.

Faculty Member Since:	1980
Degrees:	MD, BA, University of Pennsylvania
Rank:	Professor
Research Interests:	Transplantation Immunobiology Renal Transplantation in Children Immunosuppression in Pediatric Transplantation Recurrent Disease in Renal Transplantation
Current Grant Support:	Roche Bioscience Wyeth-Ayerst North American Pediatric Renal Transplant Cooperative Study National Kidney Foundation of Southern California
Teaching:	Pediatric Nephrology Fellowship Training Program Medical Student Advisor Pediatric Nephrology, 3rd Year Medical Student Care Lecturer Resident Conference Lecturer Attending Physician, UCLA Children's Hospital
University Service:	Academic Senate, Legislative Assembly Clinical Effectiveness Committee Clinical Laboratories Executive Committee Pediatric Quality Assurance Committee Co-Chair, Pediatric Multi-disciplinary Committee Pediatric Grand Rounds Committee Pediatric Treatment Evaluation Committee Chair, Pediatric Credentials Committee Pediatric Utilization Management Action Group Pediatrics Group Practice Plan Executive Board Pay Plan Subcommittee At Large Member, Board of UCLA Medical Group Chair, By Laws Committee Renal Transplant Executive Committee MediCare Teaching Physician Regulation Task Forces (Gold and Blue) LCME Committee on Graduate Medical Education/Clinical Teaching Facilities/Continuing Medical Education
Professional Committees:	U.S. Food and Drug Administration, Consultant Biological Response Modifier, Advisory Committee for Drug Evaluation and Research U.S. Food and Drug Administration, Consultant, Immunosuppressive Drugs Advisory Committee for Drug Evaluation and Research American Society of Pediatric Nephrology, Workforce Committee, Co-chair Fellowship Training Committee American Society of Transplant Physicians Scientific Studies Committee Society for Pediatric Research, Abstract Referee Second International Congress of Pediatric Transplantation, Organizing Committee
Honors:	Who's Who In The United States Who's Who In North America Best Doctors In America: Pacific and Western United States Who's Who in Medicine and Healthcare Best Doctors In America Best Doctors In Los Angeles - Los Angeles Magazine

KUIZON, BEATRIZ D.

Faculty Member Since:	1997
Degrees:	MD, BS, University of the Philippines
Rank:	Clinical Instructor
Research Interests:	Renal Osteodystrophy in children with end-stage renal disease Endochondral bone formation in experimental uremia
Current Grant Support:	1995-97 National Kidney Foundation of Southern California
Teaching:	Pediatric Nephrology Fellows' Training Lectures for residents, medical students

SALUSKY, ISIDRO B.

Faculty Member Since:	1982
Degrees:	MD, National University of Buenos Aires (Argentina) BS, Institute Libre de Segunda (Argentina)
Rank:	Professor
Research Interests:	Regulation of bone formation in renal osteodystrophy. Parathyroid gland function in different types of metabolic bone diseases. Peritoneal Dialysis: a) Nutritional aspects b) Characteristics of the peritoneal membrane Training in clinical investigation.
Current Grant Support:	1986-98 PHS/National Institute of Diabetes, Digestive and Kidney Diseases 1995-98 Genentech Foundation for Growth and Development 1996-01 UCLA General Clinical Research Center/National Center for Research Resources, NIH 1996-98 Wyeth-Ayerst Research 1997-98 Hoffman La-Roche
Teaching:	Clinical Investigation for Post-Graduate medical education Fellows Training - Dialysis, Pediatric Nephrology, Metabolic Bone Diseases Metabolic Bone Diseases
University Service:	Academic Senate Faculty Executive Committee Academic Senate Faculty Executive Committee Bylaws Subcommittee Academic Senate Office of Protection of Research Subjects Task Force Academic Senate Ad-Hoc Urology Department Proposal Committee Academic Senate Long-Term Planning Committee for the General Clinical Research Center Department of Pediatrics Grand Rounds Committee: Chairman General Clinical Research Center Advisory Board Dialysis Department Quality Assurance Committee Dialysis Department Executive Administrative Committee Master Planning Committee Master Planning Research Subcommittee Clinical Trials Office Working Group Clinical Trials Unit Oversight Board: Chairman
Professional Committees:	National Kidney Foundation, Scientific Advisory Council Executive Committee National Kidney Foundation of Southern California, Council on Pediatric Nephrology & Urology National Kidney Foundation of Southern California, Region V, Nominating Committee American Board of Pediatrics, Subboard of Pediatric Nephrology North American Pediatric Renal Transplant Registry (NAPRTCS) American Society of Pediatric Nephrology, Scientific Advisory Committee International Society of Pediatric Nephrology, Research Subcommittee Council Member, International Society of Pediatric Nephrology Chairman, Pediatric Section of the 1998 ISN Conference

SANCHEZ, CHERYL P.

Faculty Member Since:	1994
Degrees:	MD, BS - University of the Philippines
Rank:	Assistant Clinical Professor
Research Interests:	Transplant Bone Disease Vitamin D and Growth Hormone in Uremic Rats Skeletal Regulation in Chronic Renal Failure
Current Grant Support:	1995-98 GCRC- NIH- Clinical Associate Physician Award 1995-1997 Genentech Foundation for Growth and Development
Teaching:	Residents' Noon Lecture Series Core lectures for medical students Fellows Teaching Renal Ward Team
University Service:	GCRC Advisory Committee

YADIN, ORA

Faculty Member Since:	1993
Degrees:	MD, The Hebrew University (Israel)
Rank:	Assistant Clinical Professor
Research Interests:	Use of recombinant human growth hormone (rhGH) to treat the short stature of children with chronic renal failure. Use of IVIg and other agents to reduce the anti-HLA antibodies of highly presensitized dialysis patients.
Current Grant Support:	1996-00 NIH/Southwest Pediatric Nephrology Study group
Teaching:	Grand Rounds

DIVISION PUBLICATIONS:

1. Al-Akash S, Ettenger RB. Immunosuppression in the pediatric population. Current Opinion in Organ Transplantation 2:89-96, 1997.
2. Alexander SR, Salusky IB, Warady BA, Watkins SL. Peritoneal Dialysis Workshop: Pediatric Recommendations. Amer. J Kidney Diseases 17(S3):S25-S27, 1997.
3. Aufricht C, Hogan EL, Ettenger RB. Oral Metronidazol does not Improve Cyclosporine A - induced Gingival Hyperplasia. Pediatric Nephrology. 11:552-555 1997.
4. Aufricht C, Marik JL, Ettenger RB. Subcutaneous recombinant human erythropoietin in children with chronic renal allograft dysfunction. (in press, Pediatric Nephrology).
5. Coburn JW, Goodman WG, Salusky IB. Renal bone diseases and aluminum toxicity in renal patients. In: Caring for the Renal Patient, 3rd ed. (ed.) by Levine DZ, W.B. Saunders Co., Philadelphia. pp. 168-183, 1997.
6. Ettenger RB, Cohen A, Nast C, Moulton L, Marik J, Gales B. Mycophenolate Mofetil (MMF) as maintenance immunosuppression in pediatric renal transplantation Transplantation Proceedings. 29:340-341, 1997.
7. Ettenger RB, Kamal SS. The Use of Neoral in Pediatric Kidney Transplantation. Transplantation & Immunology Letter. 8:5-10. 1997.
8. Goodman WG, Veldhuis JD, Belin TR, Juppner H, Salusky IB. Suppressive effect of calcium on parathyroid hormone release in adynamic renal osteodystrophy and secondary hyperparathyroidism. Kidney Int 51:1590-1595, 1997.
9. Greenbaum LA, Ettenger RB. Acute Pericarditis following bilateral kidney embolization. Pediatric Nephrology. 11: 658-660,1997
10. Holloway M, Salusky IB. The impact of end-stage renal disease in children and family. American Kidney Foundation. (In press)
11. Kuizon BD and Salusky IB. Aluminum and bone disease in children with renal failure. In: Aluminum toxicity in infant health and nutrition. (ed.) by Alfrey AC and Zatta PF, World Scientific, London. (In press)
12. Kuizon BD and Salusky IB. Diagnosis and treatment of renal bone diseases in children ungergoing CAPD/CCPD. In: CAPD/CCCPD in children. (ed.) by Fine RN, Alexander SR and Warady B, Kluwer Academic Publishers, Norwell. (In press)
13. Kuizon BD and Salusky IB. Intermittent calcitriol therapy and growth in children with chronic renal failure. Mineral and Electrolyte Metabolism (In press)
14. Kuizon BD, Goodman WG, Juppner H, Salusky IB. Diminished linear growth during treatment with intermittent calcitriol and dialysis in children with chronic renal failure. Kidney Int. (In press)
15. Kuizon BD, Nelson PA, Salusky IB. Tube feeding in children with end stage renal disease. Mineral and Electrolyte Metabolism 23(3-6):306-310, 1997.
16. Oppenheim WL, Fischer SR, Salusky IB. Surgical correction of angular deformity of the knee in children with renal osteodystrophy. J. of Pediatric Orthopedics 17:41-49, 1997.
17. Salusky IB and Holloway M. Selection of peritoneal dialysis for pediatric patients. Amer. J Kidney Diseases 17(S3): S35-S37, 1997.
18. Salusky IB, Foley J, Goodman WG. Hyperparathyroid bone disease response to oral calcitriol and calcium carbonate in children on CAPD/CCPD. Am. J. Kidney Dis. (In press)
19. Sanchez CP and Salusky IB. Bone and mineral metabolism in children with chronic renal failure. In: Renal Osteodystrophy. (ed.) by Bushinsky DA, Lippincott-Raven, Philadelphia. (In press).
20. Sanchez CP, Goodman WG and Salusky IB. Renal osteodystrophies: Pathogenesis and treatment. In: Pediatric Nephrology, 4th ed. (ed.) by Barrat TM, Avner ED, and Harmon W, Williams & Wilkins, Baltimore. (In press)
21. Sanchez CP, Salusky IB, , Kuizon BD, Ramirez JA, Gales B, Ettenger RB, Goodman WG. Bone disease in children and adolescents undergoing successful renal transplantation. Kidney Int, in press.
22. Simoni JM, Asarnow JR, Munford PR, Koprowski CM, Belin TR, Salusky IB. Psychological distress and treatment adherence among children on dialysis. Pediatric Nephrology 11:604-606, 1997.
23. Stapleton FB, Andreoli S, Ettenger RB, Kamil E, Sedman A, Chesney R. Future Workforce Needs for Pediatric Nephrology: An Analysis of the Nephrology Workforce and Training Requirements by the Workforce Committee of the American Society of Pediatric Nephrology. Journal of the American Society of Nephrology 8: S5-8, 1997.
24. Tan PM, Yadin O, Kleinman K, Gura V and Cohen A. Simultaneous Postinfectious Glomerulonephritis and Thrombotic Microangiopathy: A Renal Biopsy Study. Am J Kidney Dis (Accepted for publication).
25. Turenne MN, Port FK, Strawderman RL, Ettenger RB, Alexander SR, Lewy JE, Jones CA, Agodoa LY, Held PJ. Growth Rates in Pediatric Dialysis Patients and Renal Transplant Recipients. Amer. Jour of Kidney Disease. 30:193-203 1997.
26. von Lilien T, Salusky IB. Growth in children undergoing continuous ambulatory or cycling peritoneal dialysis. In: Endocrinology. (ed.) by Scharer K, Springer-Verlag, Heidelberg. (In press)
27. Yadin O and Fine R. Long-term use of recombinant human growth hormone (rhGH) in children with chronic renal insufficiency. Kidney Int (1997) Vol 51, Suppl 58 S102-105.