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DIVISION OF
NEPHROLOGY
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Nephrology Team |
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Back Row: JoAnn Foley, Jennifer
Marik, E. Brophy, Yolanda Tejedor, R. Larner.
Middle Row: Barbara Gales, Rita Davila, Julia
Saulny, Robert Ettenger, Judith Smith, S. Barayan, Alan Shapiro.
Front Row: Isidro Salusky, Joma
Mahdavi, S. Garaybeh, Ora Yadin, Beatriz Quizon, C. Dominguez.
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Faculty
Profiles
AL-AKASH, SAMHAR I.
| Faculty Member
Since: |
1999 |
| Degrees: |
MD, BA, University of Jordan School of Medicine |
| Rank: |
Clinical Instructor |
| Research
Interests: |
Transplant immunology |
| Teaching: |
Medical Student Core Lecture Series
Pediatric Noon Conference |
ETTENGER, ROBERT B.
| Faculty Member
Since: |
1980 |
| Degrees: |
MD, University of Pennsylvania
BA, University of Pennsylvania |
| Rank: |
Professor |
| Research
Interests: |
Pediatric renal transplant, immunosuppressive Drugs |
| University
Service: |
Academic Senate, Legislative Assembly
Dialysis and Transplant Committee
Blood & Blood Derivatives Committee
Medical Staff Credentialing Committee
Clinical Effectiveness Committee
Clinical Laboratories Activities Committee
Co-Chair, Pediatric Multidisciplinary Committee
Quality Assurance Committee
Grand Rounds Committee
Chair, Continuing Education Committee
Chair, Credentials Committee
Department Group Practice Plan
Executive Board
Chair, Adolescent Ward Reorganization Committee
Chair, Department Compliance Committee
Chair, Performance Improvement Team Committee
Review and Appraisal Committee
Medicare Teaching Physician Regulation Task Force
Compliance Committee
Master Planning Phase II
Board of the UCLA Medical Group, At-Large Member
Clinical Effectiveness Committee
Chair, By-Laws Committee |
| Grant Support: |
1994-Present North American Pediatric Renal Transplant Cooperative
Study. Emmes Corporation
1997-99 A Phase I/II Study of Zenapax® in Pediatric Patients.
Hoffmann-La Roche, Inc.
1997-99 Oral Suspension in
Mycophenolate, Roche Laboratories
1997-PresentThe Use of Recombinant Human Growth Hormone
(Nutropin)
in Children Post-Renal Transplantation, North American Pediatric
Renal Transplant Cooperative Study
1998-2000 Influenza Vaccine Antibody Response in Pediatric Renal
Transplant Patients Treated with Newer Immunosuppressive
Agents, Hoffmann-LaRoche, Inc.
1996-2000 Donor-specific hyporesponsiveness in Mixed Lymphocyte
Culture in patients receiving Mycophenolate
Mofetil, Hoffman-La
Roche
1998-2002 An Open-Label Safety Tolerance and Pharmacokinetic
Study of Oral Mycophenolate Mofetil, suspension in the Prophylaxis of
Rejection in Pediatric Renal Allograft Recipients, Hoffman-La
Roche
1999-2002 Collaborative Clinical Trial in Transplantation
(CCTT); the use
of Sirolimus in the treatment of chronic rejection of pediatric
renal transplants, Wyeth Ayerst Laboratories
1999-2000
Multicenter, Open-Label, Single Oral Dose Pharmacokinetic,
Safety, and Tolerability Study of RAD001, Novartis Pharmaceuticals |
| Professional
Committees: |
1994-present United States Renal Data System Scientific Advisory Committee
Food and Drug Administration, Consultant, Biological Response Modifier
Advisory Committee for Drug Evaluation and Research
Food and Drug Administration, Consultant, Immunosuppressive Drugs
Advisory Committee for Drug Evaluation and Research
American Society of Pediatric Nephrology:
Membership Committee
Co-Chair, Task Force on Nephrology Physician Needs
Co-Chair, Workforce Committee
American Society of Transplant Physicians:
Awards Committee
ASTP Scientific Studies Committee
United Network for Organ Sharing:
Membership and Professional Standards Committee
World Children's Transplant Fund, Medical Board of Advisors
Santa Monica-Malibu Unified Schl Dist./ Sports & Physical Ed Advisory
Committee
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KUIZON, BEATRIZ D.
| Faculty Member Since: |
1997 |
| Degrees: |
MD, BS, University of the Philippines |
| Rank: |
Assistant Professor |
| Research Interests: |
Renal osteodystrophy in children with end-stage renal disease
Endochondral bone formation in renal failure
Vascular calcification in renal failure
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| Current Grant Support: |
1998-00 Hilda Gershon Young Investigator Grant of the National
Kidney Foundation |
| Teaching: |
Pediatric Nephrology Fellows' Training
Lectures for Residents, Medical Students
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| University Service: |
General Clinical Research Center Advisory Board |
SALUSKY, ISIDRO
| Faculty Member Since: |
1982 |
| Degrees: |
MD, National University of Buenos Aires
BS, Institute Libre de Segunda
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| Rank: |
Professor of
Pediatrics |
| Research Interests: |
Understanding treatment of bone related
abnormalities that are present in children with renal failure, characterize the
spectrum of renal osteodystropy in patients, growth and nutrition in patients
with renal failure. |
| Grant Support: |
12/1/96-11/30/01, National Center for Research.
Resources, NIH. UCLA General Clinical Research Center.
2/1/98-1/31/02 National
Institutes of Health, Diurnal and Pulsatile PTH Secretion in Renal Failure
1/1/98-12/31/00 National
Institutes of Health, Exploratory Grants in Chronic Renal Failure in Children,
Endochondral bone formation in renal failure
12/1/98-11/30/03 National
Institutes of Health, Regulation of skeletal growth in renal failure
1/1/95-3/30/00 National
Institutes of Health, Regulation of Bone
Formation in Renal
Osteodystropy
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| Teaching: |
Course
Director, "Introduction to Clinical Investigation" for
Fellows and Junior Faculty |
| University Service: |
Department of Pediatrics:
Chairman, Grand Rounds Committee
Executive Committee
School of Medicine:
Member, Long-Term Advisory Clinical Research Center Committee Member, Advisory Committee
Clinical Research Center Chair, Clinical Trials Unit Oversight Board Clinical
Research Committee Co-Chair
Medical Center:
Member,
Quality Assurance Committee, Dialysis Department Member, Executive
Administrative Committee for the Dialysis Dept
Master Planning
Committee for the New UCLA Hospital
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| Organizations: |
American Board of Pediatrics
Member, Subboard of Pediatric Nephrology Chairman, Subboard Council Member,
International Pediatric Nephrology Association Member, Research Committee,
American Society Pediatric Nephrology
General
Clinical Research Center
Program
Directors Association, Executive Committee
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| Honors: |
National Kidney Foundation, Inc.
1999 President's Award
American Medical Association
1999-2002 Physicians' Recognition Award
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YADIN, ORA
| Faculty Member Since: |
1993 |
| Degrees: |
MD, The Hebrew University
(Israel) |
| Rank: |
Assistant Professor |
| Research Interests: |
Efficacy of different therapies for IgA nephropathy, dosing, safety and
efficacy of Felodipine in children with hypertension, mycophenolate
mofetil for treatment of children with steroid resistant idipathis nephrotic
syndrome, molecular genetics and clinical presentations of the different
mutations of Bartter's and Gitelman's syndromes. |
| Grant Support: |
NIH Grant "A randomized, Placebo-controlled, Multicenter trial evaluating:
A) Alternate-day Prednisone B) Fish oil Supplements in Young
Patients with IgA Nephropathy".
12/99-10/00 "Dose ranging, Safety and Tolerability Trial of Felodipine
ER in Pediatric Patients". Sponsored by
AstraZeneca, Inc.
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| Teaching: |
Core lectures
Noon conference
Pediatric Board Review Course, UCLA
Renal Grand Rounds
Renal pathophysiology course, Wadsworth VAMC
Teaching for pediatricians, pediatric residents and medical students at
Kern County Medical Center
Teaching for Family practice residents at Ventura County Medical Center
Pediatric Specialty clinic
Lectures at Community Hospitals:
Recent advances in the treatment of UTI in children. Guest
speaker at the Education Program: Queen of the Valley Medical
Center, West Covina, CA.
A practical approach to the evaluation of hematuria in children. Downey
Community Hospital Education Program. Downey, CA.
Childhood nephrotic syndrome. Pediatric noon conference Kaiser
Permanente, Bellflower, CA.
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| University Service: |
Quality Improvement Committee, Dept of Pediarics |
| Professional Committees: |
Southern California Pediatric Nephrology Association Steering Committee
Chairperson, National Kidney Foundation Patient Education Conference,
UCLA May 1999
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Division
Publications
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Borradori Tolsa C, Kuizon
BD, Salusky IB. Children with chronic renal failure: evaluation of the
nutritional status and management. Arch Pediatr 6:1092-1100, 1999.
- Brown SB, Pike JW, Palanisamy N, Salusky
IB, Goodman W, Brandi ML, Drueke TB, Sarfati E,
Urena P,Delmonica F, Chaganti RSK, Arnold A: Vitamin D receptor as a candidate tumor suppressor gene
in severe hyperparathyroidism of uremia. J Clin Endocrin Metab. (In Press, 1999)
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Drueke TB and Salusky IB (ed). The spectrum of renal
osteodystrophy. Oxford University Press.
(In Press, 1999)
- Ettenger R. Antibody Therapy as an Induction Regimen in Pediatric Renal Transplantation.
Transplantation Proceedings. 31: 2677-2678, 1999.
- Goodman WG, Coburn JW, Slatopolsky E, Salusky
IB. Renal osteodystrophy in adult and pediatric
patients, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism,
4th Ed., edited by M Favus. Lippincott Williams & Wilkins, New York. pp. 347-363, 1999.
- Holloway M, Salusky IB. The impact of end-stage renal disease in children and family. American
Kidney Foundation. (In press, 1999)
- John MR, Goodman WG, Gao P, Cantor TL, Salusky
IB, Juppner H: A Novel Immunoradiometric
Assay Detects Full-Length Human PTH but not Amino-Terminally Truncated Fragments: Implications for
PTH Measurements in Renal Failure. J Clin Endocrin Metab: 84: 4287-4290, 1999.
- Kuizon BD, Salusky IB. Growth retardation in children with chronic renal failure. J Bone and
Mineral Res. 14: 1680-1690, 1999.
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Kuizon BD, Salusky
IB. Bone diseases in children with chronic renal failure. In Nefrologia
Pediatrica, Garcia-Nieto V, Santos Fernando, eds. Granada, Spain: Editorial
Comares, (in press, 2000)
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Kuizon BD, Salusky
IB. Growth retardation in children with chronic renal failure. JBMR 14:1680-1690, 1999.
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Kuizon BD, Salusky
IB. Renal bone diseases in children with end stage renal disease. In Atualidades
em Nefrologia Pediatrica, Perrone H, ed. (in press, 2000)
- Salusky IB, Goodman WG and Coburn JW: The renal
osteodystrophies. In: Endocrinology, 4th ed. (ed.)
by Potts JT. W.B. Saunders Company, Philadelphia. (In press, 1999)
- Salusky IB, Goodman WG, Kuizon BD. Consequences of intermittent calcitriol therapy in pediatric
patients with secondary hyperparathyroidism. Peritoneal Dialysis International 19
(Suppl
2):S441-S444, 1999.
- Salusky IB, Goodman WG, Kuizon BD. Implications of intermittent calcitriol therapy on growth
and secondary hyperparathyroidism. Pediatr Nephrol (in press, 2000)
- Salusky IB, Holloway M, Kuizon BD. Peritoneal dialysis in children: Issues for the
21st century. Peritoneal Dialysis International 19(Suppl 2): S484-S487, 1999.
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Salusky IB, Holloway M,
Kuizon BD. Peritoneal dialysis in children: Issues for the
21st century. Ped Dial Int 19 Suppl 2:S484-488, 1999.
- Sanchez CP, Goodman WG and Salusky IB. Renal
osteodystrophies: Pathogenesis and treatment.
In: Pediatric Nephrology, 4th ed. (ed.) by Barrat TM, Avner ED, and Harmon W.
Lippincott, Williams &
Wilkins, Baltimore. pp. 1231-1250, 1999.
- Sanchez CP, Goodman WG, Salusky IB. Prevention of renal osteodystrophy in predialysis patients. Am.
J. Med. Sci. 317(6):398-404, 1999.
- Sanchez CP, Kuizon BD, Abdella PA, Jüppner H,
Salusky IB, Goodman WG. Impaired growth,
delayed ossfication and reduced osteoclastic activity in the growth plate of calcium-supplemented rats with
renal failure. Endocrinology (in press, 2000)
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Von Lilien T, Salusky IB. Growth in children undergoing continuous ambulatory or cycling
peritoneal dialysis. In: Endocrinology. (ed.) by Scharer K, Springer-Verlag, Heidelberg. (In press, 1999)
- Warady BA, Fivush B, Andreoli SP, Kohaut E, Salusky
IB, Schlichting L, Pu K, Watkins S:
Longitudinal evaluation of transport kinetics in children receiving peritoneal dialysis. Pediatr Nephrol
13:571-576, 1999.
- Wolfe R, Ashby V, Milford E, Ojo A, Ettenger
R, Agodoa L, Held P, Port F: Comparison of Mortality in
All Patients On Dialysis, Patients On Dialysis Awaiting Transplantation, and Recipients of A First
Cadaveric Transplant. New England Journal of Medicine 341,23: 1725-1730, 1999.
Division
Presentations
- Al-Akash S. UCLA Experience with Daclizumab
(Zenapax) in Pediatric Renal Transplant
Recipients. Abstract presented at the 17th annual meeting of the American Society of Transplantation, 5/99.
- Al-Akash S. Pediatric Urinary Tract Infections. The UCLA Family Practice Review Course.
Santa Monica, CA, 5/28/99.
- Ettenger R. Invited Lecturer: "The Use of Daclizumab in Pediatric Renal Transplantation",
Eurotransplant Winter Meeting, Fügen, Austria, 1/99.
- Ettenger R. Invited Lecturer: "Urinary Tract Infections in Children" St. John's Hospital, Santa
Monica CA, 1/99.
- Ettenger R. Grand Rounds: "Hematuria" Kaiser
Permanente/SCPMG, West Los Angeles, CA 2/99.
- Ettenger R. Invited Lecturer: "Fluids and Electrolytes in Children" Citrus Valley Medical Center,
West Covina, CA. 3/22/99.
- Ettenger R. Invited Lecturer: "Use of Zenapax in Pediatric Renal Transplantation" St. Louis
Children's Hospital and Cardinal Glennon Children's Hospital, St. Louis, MO. 3/30-3/31/99.
- Ettenger R. Grand Rounds: "Urinary Tract Infection in Children", Olive View Medical Center,
Department of Pediatrics, Sylmar, CA. 4/14/99.
- Ettenger R. Invited Lecturer: "Renal Post Course" Princess Margaret Children's Hospital, Hong Kong
6/21-6/25/99.
- Ettenger R. Grand Rounds: "Urinary Tract Infection in Children" Kaiser
Permanente/SCPMG, West
Los Angeles, CA 9/14/99.
- Ettenger R. Invited Lecturer: "Pediatric UTI's in Primary Care" Downey Community Hospital, Downey CA.
10/8/99.
- Ettenger R. Invited Lecturer: "Urinary Tract Infections in Children", UCLA Department of Pediatrics
_ Pediatric Update Conference, Portofino Inn, Redondo Beach, CA. 10/19/99.
- Ettenger R. Instructor: "PREP: The Course." American Medical Association. 10/24/99.
- Ettenger R. Invited Lecturer: "Hypertension in Children" 17th Annual Care of the Sick Children
Conference, Orlando Regional HealthCare, Orlando, FLA, 11/9/99.
- Ettenger R. Instructor: X Brazilian Congress of Pediatric Nephrology, Sao Paulo, Brazil, 11/17-11/20/99.
- Ettenger R, Menster M, Warshaw B, Potter D, Ramos E. The Long-Term Use of Mycophenolate Mofetil
in Pediatric Renal Transplantation. A Report of the Pediatric Mycophenolate Mofetil Study Group
(PMMSG).
ASTP 18th Annual Scientific Meeting, Chicago IL, presented 5/99.
- Nevins T, Ettenger R, Potter D, Pescovitz M, Knechtle S, Colombani P, Alexander S, Ramos E.
Daclizumab
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(Zenapax) In Pediatric Renal Allografts: Final Data. ASTP 18th Annual Scientific Meeting, Chicago
IL, presented 5/99.
- Al-Akash S, Marik J, Ettenger R. Daclizumab
(Zenapax) in Pediatric (PED) Renal Transplantation
At UCLA. ASTP 18th Annual Scientific Meeting, Chicago IL, 5/99.
- Sherbotie J, Bunchman T, Navarro M, Broyer M, Chavers B, Tonshoff B, Grimm P, Lerner G, Lirenman
D, Greenbaum L, Walker R, Zimmerhackle L, Blowey D, Clark G,
Ettenger R, Ramos E for the MMF Suspension Pediatric Renal Transplant Group. Mycophenolate Mofetil
(MMF) Oral Suspension in Pediatric
Renal Transplantation. ASTP 18th Annual Scientific Meeting, Chicago IL, presented 5/99.
- Broyer M, Bunchman T, Navarro M, Sherbotie J, Chavers B, Tonshoff B, Grimm P, Lerner G, Lirenman
D, Greenbaum L, Walker R, Zimmerhackl L, Blowey D, Clark G,
Ettenger R and Ramos E for the MMF Suspension Pediatric Renal Transplantation. Preliminary
Pharmacokinetics, Safety and Efficacy
of Mycophenolate Mofetil (MMF) Oral Suspension in Pediatric Renal Transplantation9th Congress of
the European Society for Organ Transplantation, Oslo Norway, 5/99.
- Ettenger R, Nevins T, Potter D, Pescovitz M, Knechtle S, Colombani P, Alexander S, Ramos E.
Daclizumab (Zenapax) in Pediatric Renal Transplantation. 9th Congress of the European Society for Organ
Transplantation, Oslo Norway, presented 6/99.
- Kuizon BD, Goodman WG, Gales B, Juppner H and
Salusky IB: Skeletal effects of growth hormone
and calcitriol in children with ESRD. The American Pediatric Society and The Society for Pediatric
Research, 1999.
- Sanchez CP, Goodman WG, Kuizon BD, Gales B,
Ettenger RB and Salusky IB: Twelve months of
growth hormone therapy does not improve bone mass or bone formation rate in pediatric kidney recipients.
The American Society for Bone and Mineral Research 21st Annual Meeting, 1999.
- Kuizon BD, Salusky IB, Sanchez CP, Juppner H and Goodman
WG. Assessment of renal
osteodystrophy using in situ hybridization in human growth plate cartilage. The American Society for Bone and
Mineral Research 21st Annual Meeting, 1999.
- Imanishi Y, Tahara H, Salusky I, Goodman W, Brandu ML, Drueke TB, Sarfati E, Urena P and Arnold A.
Gene mutations in refractory hyperparathyroidism of uremia. The American Society for Bone and
Mineral Research 21st Annual Meeting, 1999.
- Lima EM, Kuizon BD, Gales B, Goldin J,
Salusky IB and Goodman WG. Non-invasive assessment of
renal osteodystrophy in pediatric dialysis patients using peripheral quantitative computed tomography
(pQCT).
American Society of Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Lima EM, Kuizon BD, Gales B, Goldin J,
Salusky IB and Goodman WG. Assessment of bone mineral
density using peripheral quantitative computed tomography (pQCT) in pediatric renal transplant recipients.
American Society of Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Kuizon BD, Goodman WG, Gales B, Sahney S, Juppner H and
Salusky IB. The impact of growth hormone therapy on the treatment of renal osteodystrophy in children on
CCPD. American Society of
Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Kuizon BD, Salusky IB, Sanchez CP, Willsey P, Cambay E, Juppner H and Goodman
WG. Changes
in growth plate morphology and chrondocyte proliferation in adynamic bone due to high dietary
calcium intake. American Society of Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Kuizon BD, Salusky IB, Sanchez CP, Juppner H and Goodman
WG. Assessment of molecular markers
of endochondral bone formation in growth plate cartilage of children with renal bone disease.
American Society of Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Sanchez CP, Goodman WG, Kuizon BD, Gales B,
Ettenger RB, and Salusky IB. Bone mass, bone
histology
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and growth hormone therapy in pediatric patients after kidney transplantation. American Society
of Nephrology 32nd Annual Meeting and Scientific Exposition 1999.
- Sanchez CP, Goodman WG, Kuizon BD, Gales B,
Ettenger RB and Salusky IB. The skeletal effects
of immunosuppression in children with stable kidney transplant. American Society of Nephrology 32nd
Annual Meeting and Scientific Exposition 1999.
- Salusky IB. New York Society of Nephrology, New York, New York, Lecture: "Consequences of
calcitriol therapy on growth and bone." 1/13/99.
- Salusky IB. Southern California Permanente Medical Group's 1999 Nephrology Symposium, Universal
City, California, Lecture: "Management of bone disease in the ESRD population." 5/2-5/6/99.
- Salusky IB. Sixth Symposium on Growth and Development in Children with Chronic Renal Failure,
New York, New York, 3/11-3/13/99.
- Salusky IB. XVth International Congress of Nephrology. XIth LatinAmerican Congress of
Nephrology, Buenos Aires, Argentina, Invited Speaker for "Symposium on Renal Osteodystrophy"Lecture: "The
therapeutic approach to renal osteodystrophy in pediatric patients." 5/2-5/6/99.
- Salusky IB. Official Satellite Symposium of the XVth International Congress of Nephrology: "Advances
in the Pathogenesis and Treatment of Renal Osteodystrophy," Foz do Iguazu,
Brasil, Invited Speaker
for "The Effects of Growth and Acidosis on Bone in Renal Failure" Lecture: "Growth and bone in renal
failure" 5/7-5/9/99.
- Salusky IB. A Pediatric Nephrology Educational Conference for Children and Their Families Coping
With Kidney Disease, Los Angeles, California, Lecture: "Diferentes tipos de dialisis" 5/23/99.
- Salusky IB. Nephrology Grand Rounds, Division of Nephrology and Hypertension, LAC
Harbor-UCLA Medical Center, Torrance, California, Lecture: "The impact of growth hormone therapy on renal
osteodystrophy" 6/14/99.
- Salusky IB. Kaiser Permanente Pediatric Nephrologists Meeting, Pasadena, California,
- Bone Care Symposium. Lecture: "Management of chronic renal failure in children: Different aspects"
7/6/99.
- Salusky IB. American Society of Nephrology 32nd Annual Meeting, Miami, Florida, Invited Speaker
for "Renal Bone Disease" 11/8/99.
- Salusky IB. Lecture: "Mechanisms and biochemical predictors of a dynamic bone disease" 1999.
- Salusky IB. Pugue European Society of Pediatrics Nephrology. Invited Speaker, 1999.
- Yadin O. A randomized, Placebo-controlled, Multicenter trial evaluating: A) Alternate-day Prednisone
B) Fish oil Supplements in Young Patients with IgA Nephropathy. Renal Grand Rounds Wadsworth
VAMC,
9/30/99.
- Yadin O. IgA Nephropathy on its 30th anniversary: what have we learned? Renal Grand Rounds,
Cedars-Sinai Medical Center. 10/5/99.
- Lande M, Guillion C, Roth L, Roy S, Gauthier B, Strife F, Gray J, Nash M,
Yadin O, Gharaybeh S, Bonilla-Felix M, Diven S and Leonard M. Long versus standard prednisone therapy in children with
steroid-sensitive nephrotic syndrome (SSNS). International Pediatric Nephrology Association meeting, London,
UK, 9/99.
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